In this activity, learners model directed evolution by making paper fly. Learners construct and fly paper airplanes. During the first round, they calculate the average distance the planes fly and then recreate the planes that flew the furthest. Learners repeat this process several times, observe how the average distance of flight changes, and eventually identify the ideal flyer. This activity can be used to introduce learners to genetic random mutations and how scientists are using directed evolution to engineer new proteins with enhanced properties.