This lesson is the first of a two-part series on laughter and how it can affect the immune system. In this lesson, students explore gelotology (the science of laughter) and its benefits to our social, mental, and physical well-being. The first lesson has a twofold focus. First, it focuses on the science of laughter in terms of how the brain reacts to an external stimulus that is funny. Second, it explores the positive effects of laughter in terms of our social, mental, and physical well-being.